HITBox 06 · Strength & Energy
Endurance, tone and clear mind — without burnout
19 000 ₽
Quantity
1
For Research Use Only. Not for human consumption.
19 000 ₽
Box 06 · Strength & Energy
Formulation: MOTS-C 10 mg · SS-31 10 mg · CJC-1295 + Ipamorelin 10 mg · Thymosin Alpha-1 10 mg · Semax 11 mg · BAC Water 3 ml × 5
Purity: ≥99.0% (HPLC)
Storage: −20 °C (before opening), +2…+8 °C (after reconstitution, no longer than 28 days)
Contents
- What this box is for
- MOTS-C — energy at the mitochondrial level
- SS-31 — stabilization of mitochondrial membranes
- CJC-1295 + Ipamorelin — natural rise in growth hormone
- Thymosin Alpha-1 — conductor of the immune system
- Semax — mental clarity and neuroplasticity
- How the components complement one another
- Value in this box
- References
1. What this box is for
The largest box in the catalog — five peptides, four directions: cellular energetics, muscle tone, immunity, cognitive function. A steady resource for the whole day.
The scientific literature discusses how, after the age of 40–45, several markers decline at once: the mitochondria work less efficiently, endogenous growth hormone falls, the immune response weakens (thymic involution), and cognitive function slows (BDNF declines). The five peptides in this box are studied in each of these directions.
2. MOTS-C — energy at the mitochondrial level
MOTS-C is a 16-amino-acid peptide encoded by mitochondrial DNA. It is one of the few known peptides produced not by the nuclear genome but by the mitochondria — the cell's "power stations."
In the study by Lee C. et al. (Cell Metabolism, 2015), MOTS-C was shown to influence glucose metabolism and the activation of the AMPK pathway — a key regulator of cellular energetics. In experimental models, an increase in insulin sensitivity and improved glucose processing were observed [1].
MOTS-C concentration in the body declines with age. Within this box, MOTS-C is the first of two mitochondrial peptides: it is studied for the activation of cellular energetics via the AMPK pathway.
3. SS-31 — stabilization of mitochondrial membranes
SS-31 (Elamipretide) is a tetrapeptide that works not outside the cell but within it — directly in the mitochondria. Unlike most peptides, SS-31 does not interact with receptors on the cell surface. It enters the cell and binds to cardiolipin, a key component of the inner mitochondrial membrane.
Stabilization of cardiolipin is discussed in the scientific literature as a way to support mitochondrial function. In studies by Szeto H.H. et al., restoration of mitochondrial bioenergetics was observed across various experimental models [2].
Paired with MOTS-C, the result is two mitochondrial peptides with different mechanisms: MOTS-C activates the AMPK pathway, while SS-31 stabilizes the membranes. Two approaches to one task — cellular energetics.
4. CJC-1295 + Ipamorelin — natural rise in growth hormone
Two peptides that work as a pair. CJC-1295 is a modified analogue of growth-hormone-releasing hormone (GHRH), while Ipamorelin is a selective secretagogue acting through the ghrelin receptor. Together they are studied for their capacity to stimulate the body's own growth-hormone production gently and physiologically.
In the study by Teichman S.L. et al. (J Clin Endocrinol Metab, 2006), CJC-1295 was shown to provide prolonged stimulation of GH and IGF-1 secretion in healthy adults [3]. Ipamorelin is distinguished by high selectivity — in studies, minimal influence on cortisol and prolactin was observed [4].
Growth hormone is linked to the maintenance of muscle mass, skin density, and overall body composition. Within this box, CJC-1295 + Ipamorelin is the support for muscle tone and physical condition.
5. Thymosin Alpha-1 — conductor of the immune system
One of the most extensively studied immune peptides in the world. Thymosin Alpha-1 is a 28-amino-acid peptide produced naturally by the thymus. With age the thymus shrinks (involution), and the production of Thymosin Alpha-1 declines.
What sets this peptide apart is immunomodulation: it does not merely stimulate immunity but maintains the balance between activation and suppression of the immune response. In studies, an influence on the maturation of dendritic cells and the activation of T-lymphocytes was noted [5].
Within this box, Thymosin Alpha-1 accounts for the immune dimension: steady immunity is the foundation without which neither energy nor tone carries meaning.
6. Semax — mental clarity and neuroplasticity
A Russian nootropic peptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. Semax is a synthetic analogue of the ACTH (4–10) fragment, studied for its capacity to influence memory, concentration, and resilience to stress.
Studies note its potential to raise levels of BDNF — a neurotrophic factor linked to neuroplasticity, the brain's ability to form new neural connections. Activation of the brain's dopaminergic and serotonergic systems was observed [6].
Within this box, Semax is the cognitive dimension: a clear head and concentration as part of the overall resource, alongside energy, tone, and immunity.
7. How the components complement one another
Five components — four directions: energy, tone, immunity, brain.
| Component | Research focus |
|---|---|
| MOTS-C | Cellular energetics: AMPK pathway, glucose metabolism |
| SS-31 | Mitochondrial stability: cardiolipin, bioenergetics |
| CJC-1295 + Ipamorelin | Growth hormone: muscle tone, body composition |
| Thymosin Alpha-1 | Immunomodulation: T-cells, balance of the immune response |
| Semax | Cognitive function: BDNF, neuroplasticity, concentration |
The most comprehensive box in the catalog. Each peptide is studied in its own direction, yet all five are united by a single idea: a steady resource for the body — energy, strength, protection, clarity.
8. Value in this box
| Value | |
|---|---|
| Bought separately | 22 400 ₽ |
| Box price | 19 000 ₽ |
| Discount | 3 400 ₽ |
| BAC Water included free (5 × 500 ₽) | 2 500 ₽ |
| Total value | 5 900 ₽ (26%) |
9. References
[1] Lee C. et al. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metab. 2015;21(3):443–454. PMID: 25738459
[2] Szeto H.H. First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics. Br J Pharmacol. 2014;171(8):2029–2050. PMID: 24117165
[3] Teichman S.L. et al. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295. J Clin Endocrinol Metab. 2006;91(3):799–805. PMID: 16352683
[4] Raun K. et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552–561. PMID: 9849822
[5] Romani L. et al. Thymosin alpha1: an endogenous regulator of inflammation, immunity, and tolerance. Ann N Y Acad Sci. 2012;1270:32–36. PMID: 23050814
[6] Eremin K.O. et al. Semax, an ACTH(4-10) analogue with nootropic properties, activates dopaminergic and serotoninergic brain systems in rodents. Neurochem Res. 2005;30(12):1493–1500. PMID: 16362768
For laboratory and research use only.
For Research Use Only. Not for human consumption.