Box 01 · Slimness + Skin (Reta 10 mg)
Lose weight while looking fresh, not drawn
26 100 ₽
Quantity
1
For Research Use Only. Not for human consumption.
26 100 ₽
Box 01 · Slimness + Skin (Reta 10 mg)
Formulation: Retatrutide 10 mg · Blend Premium 80 mg (BPC-157 / TB-500 / KPV / GHK-Cu) · Glutathione 1500 mg · KPV 10 mg · BAC Water 3 ml × 4
Purity: ≥99.0% (HPLC)
Storage: −20 °C (before opening), +2…+8 °C (after reconstitution, no longer than 28 days)
Contents
- Why this box exists
- Retatrutide — a triple metabolic agonist
- Blend Premium — four peptides in one vial
- Glutathione — the cell's master antioxidant
- KPV — a peptide studied in the context of inflammation
- How the components complement one another
- Value in this box
- References
1. Why this box exists
Most research on metabolic peptides focuses on a single measure — body weight. Yet the scientific literature increasingly raises another question: what happens to skin and tissue during rapid changes in body composition.
That question shaped this box. Retatrutide is the most extensively studied triple agonist to date, drawing researchers' attention with its phase 2 results. The other three components are studied in adjacent directions: connective-tissue repair, antioxidant protection of cells, and modulation of inflammatory processes.
The box is assembled so that four research directions complement one another rather than overlap.
2. Retatrutide — a triple metabolic agonist
The next evolutionary step after tirzepatide. Retatrutide is a synthetic 39-amino-acid peptide that engages three receptors at once: GLP-1, GIP, and the glucagon receptor (GCGR). Where tirzepatide acts on two of the three, Retatrutide recruits all three — and it is the third, the glucagon receptor, that draws particular interest from researchers, since it is linked to energy expenditure and fat oxidation.
In the study by Jastreboff A.M. et al., published in The New England Journal of Medicine (2023), participants receiving Retatrutide within a phase 2 trial showed a reduction in body weight of up to 24.2% over 48 weeks. At the study's conclusion no plateau had been reached — the curve was still trending downward. This is one of the most notable results reported in the literature for this class of molecules [1].
3. Blend Premium — four peptides in one vial
Blend Premium brings together four peptides — BPC-157, TB-500, KPV, and GHK-Cu — in a single 80 mg vial. Each is studied along its own line, yet all four connect to processes of tissue repair.
BPC-157 — a pentadecapeptide isolated from gastric juice. In preclinical studies its influence on angiogenesis and repair of damaged tissue has been observed [2].
TB-500 (Thymosin β4) — a 43-amino-acid peptide involved in cell migration and differentiation. It is studied in the context of restoring the structure of skin and connective tissue [3].
GHK-Cu — a copper-binding tripeptide naturally present in blood plasma. GHK-Cu concentration declines with age. In studies its capacity to influence collagen remodeling and the activity of antioxidant enzymes has been observed [4].
KPV — a tripeptide that is a fragment of α-MSH (alpha-melanocyte-stimulating hormone). It is studied for its ability to modulate inflammatory signals at the cellular level [5].
In blend form, four mechanisms are available in one vial — logistically simpler, and it allows synergy to be researched without separate preparation.
4. Glutathione — the cell's master antioxidant
Glutathione (γ-glutamyl-cysteinyl-glycine) is a tripeptide produced in every cell of the body. Scientists call it the "master antioxidant": it does not merely neutralize free radicals itself but also regenerates other antioxidants — vitamins C and E.
Endogenous glutathione synthesis declines with age. The scientific literature discusses the link between falling glutathione levels and oxidative stress, considered one of the factors in cellular aging [6].
In the context of this box, Glutathione is studied as a complement to the metabolic peptides: support for the antioxidant defense of cells during a period of intense metabolic activity.
The 1500 mg amount is one of the most frequently encountered in research protocols.
5. KPV — a peptide studied in the context of inflammation
A small but remarkable peptide. KPV is a fragment of the hormone α-MSH (amino acids 11–13) that draws researchers' attention with its ability to modulate inflammatory signals at the cellular level.
Inflammation is one of the key factors discussed in the scientific literature in connection with the condition of skin, gut, and overall outcomes during changes in body weight. KPV is studied as a potential modulator of the NF-κB pathway — a central regulator of the inflammatory cascade [5].
Within this box, KPV complements Blend Premium: where the blend focuses on restoring tissue structure, KPV is studied in the direction of modulating the inflammatory background.
6. How the components complement one another
Each component of the box is studied along its own line, yet all four intersect on one theme: what happens to the body during a substantial change in body composition.
| Component | Research focus |
|---|---|
| Retatrutide 10 mg | Metabolic body-weight research (triple GLP-1/GIP/GCGR agonist) |
| Blend Premium | Tissue repair: collagen, angiogenesis, cell migration |
| Glutathione | Antioxidant protection of cells, detoxification |
| KPV | Modulation of inflammatory processes (NF-κB pathway) |
In the scientific literature each of these directions is discussed as an independent field. The box brings them together for researchers who study these processes in combination.
7. Value in this box
| Value | |
|---|---|
| Bought separately | 30 700 ₽ |
| Box price | 26 100 ₽ |
| Discount | 4 600 ₽ |
| BAC Water included free (4 × 500 ₽) | 2 000 ₽ |
| Total value | 6 600 ₽ (21%) |
8. References
[1] Jastreboff A.M. et al. Triple-hormone-receptor agonist retatrutide for obesity — a phase 2 trial. N Engl J Med. 2023;389(6):514–526. PMID: 37366315
[2] Sikiric P. et al. Brain-gut axis and pentadecapeptide BPC 157: theoretical and practical implications. Curr Neuropharmacol. 2016;14(8):857–865. PMID: 27306034
[3] Philp D. et al. Thymosin beta 4 promotes angiogenesis, wound healing, and hair follicle development. Ann N Y Acad Sci. 2007;1112:95–103. PMID: 17600289
[4] Pickart L. et al. GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration. Biomed Res Int. 2015;2015:648108. PMID: 26236730
[5] Kannengiesser K. et al. Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease. Inflamm Bowel Dis. 2008;14(3):324–331. PMID: 18092346
[6] Forman H.J. et al. Glutathione: overview of its protective roles, measurement, and biosynthesis. Mol Aspects Med. 2009;30(1–2):1–12. PMID: 18796312
For laboratory and research use only.
For Research Use Only. Not for human consumption.